This technique avoids 1 st pass hepatic metabolism and the enzyme degradation Gastrointestinal Tract and also avoids gastrointestinal irritation 4. Otherwise, a topical drug delivery system is a very useful and easy technique for the administration of the drug, cause in this technique the self-administration of the drug is possible. Topical medication had a serious effect on the body for avoiding it used by taking the advice of a physician. TDDS has a very fast local action on the application area or the part of the body where we applied 3. TDDS have a local effect and also a systemic effect when 2drugs reach the body’s circulation system after application to the dermis. In the topical drug delivery system (TDDS) drugs can be applied on skin that was present interiorly (mouth portion, rectal route) and also the exterior part of the body (Skin) 2. There are many common topical medications available in the market such as ointment, lotion, gels, powders, and transdermal patches. In the TDDS drug can be delivered directly onto the infected area or a body surface. For the treatment of this infection, we used the topical drug delivery system 1. It will be used for the treatment of dermal infections caused by bacteria are acne, pimples, cellulitis, fungal infection are Tinea corporis, Tinea pedis, Tinea barbae candidiasis, dermatophytosis. Topical Drug Delivery System (TDDS) has been commonly used in the field of cosmetics. A Systemic Review on Micro-emulsion: Liquid Dosage form for Topical Drug Delivery System.Biosci Biotech Res Asia 2022 19(2). A Systemic Review on Micro-emulsion: Liquid Dosage form for Topical Drug Delivery System.Biosci Biotech Res Asia 2022 19(2).ĭhanawate P. KEYWORDS: Biocompatibility Microemulsion Skin Penetration Topical Administrationĭownload this article as: Copy the following to cite this article:ĭhanawate P. There are several test frames used to maintain stability, microemulsion kinetics. Due to the presence of a hydrophilic and lipophilic environment, it provides outstanding biocompatibility. Because of this, the immediate action of the drug can occur in the infected area. MEs provide high penetration and the ability to penetrate into the skin. Microemulsion increases solubility, protects the drug from environmental factors and improves drug bioavailability. So, in this case, we used the Microemulsion-based Topical Drug Delivery system. With standard drugs, skin penetration may take time and have not been able to provide immediate action. The function of skin balance is to limit the penetration of bacteria, viruses, and other environmental factors. By improving the quality of skin texture, it provides a level of penetration. Due to its solubility, mild skin irritation, and watery swelling are used in the Topical Drug Delivery System (TDDS). Microemulsion is an attractive drug delivery system for topical administration. Microemulsions (ME) is a system that combines water, oil, and an emulsifier / surfactant which is a form of volatile liquid, homogeneous and kinetically stable. Vishwanth Karad MIT World Peace University, Kothrud, Pune, Maharashtra, India. Pratik Dilipraj Dhanawate 1, Ashwini Ramkrishana Gawade 2*, Ashwin Bhanudas Kuchekar 2 and Akash Anil Podutwar 2ġMAEER’s Maharashtra Institute of Pharmacy, Savitribai Phule Pune University, Kothrud Pune, Maharashtra, India.ĢSchool of Pharmacy Dr. A Systemic Review on Micro-emulsion: Liquid Dosage form for Topical Drug Delivery System
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